Ethyl Cellulose for pharmaceutical application
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Introduction
Name: Ethyl Cellulose
Abbreviation: EC
Structural formula:In the formula, n stands for degree of polymerization and R for –H or –C2H5.

Characteristics:
Ethyl Cellulose is a kind of white grains or powder, having no smell or tastes. Its 5% soliquoid shows neutral to litmus test paper. Its specific density 1.07~1.18, heat distortion point: 135~155degree centigrade, and fire point: 330~360 degree centigrade. Ethyl Cellulose has good stability to light, heat, oxygen and wetness, and is stable to chemicals. It is resistant to alcali, dilute acid and salting liquid, soluble in some organic solvents, such as alcohol, ether, ketone, ester, aromatic hydrocarbon and halohydrocarbon, etc, and compatible to many celluloses, resin and nearly all plasticizers. Ethyl Cellulose has low combustibility, small hydroscopicity and good electric behavior. Its thin film and plastics have good mechanical strength and flexibility in a wide range of temperature.
Technical requirements:
It conforms to WJ405-2002 requirements

1. Appearance :White or even yellowing powder or grains, having no smell or taste.
2. Technical Index

Item

Index

K type

N type

T type

Content of ethoxy, %

45.0~47.9 In it, Ka type: 45.3~46.8

48.0~49.5

>=49.6

Viscosity (1:4 ethanol-toluene solvent) mPas

Conform to the requirements of table 2

Solubility, %

≥99.0

Content of ash, %

≤0.3

Moisture content, %

≤3.0

Oversize (0.85mm mesh size), %

≤1

Heat endurance (120 16h)

No yellowing, blocking, or coking

Note 1:Item of oversize is only for powder product.
Note 2:Item of heat endurance is necessary only at the customers’ requirements.

3.Viscosity Specification
Specification

Range of viscosity

Specification

Range of viscosity

6

5.0~8.0

55

51~61

10

8.1~12

70

62~74

15

13~19

90

80~99

25

20~29

110

100~120

35

30~39

150

135~165

45

40~50

 

 

Note: Provided that buyers have other requirements, negotiation might be necessary between supplier and buyers.
Usage
Ethyl Cellulose is widely used in paints for various products, such as wooden products (furniture), metal surfaces, paper, rubber, thermotropic products and integrated circuits; in ink such as screen printing ink, magnetic ink, intaglio and amine printing ink; as freezing-resistant material and all kinds of precise membrane module used in aviation industry; as the special plastics and precipitate such as rocket propellant coating band; as electrical insulation and cable coating; as high molecular suspension polymerizing and dispersing agent; as adhensive in hard alloy and ceramics; and used as dye printing slurry in textile industry.
Package
It is packed in paper bags, fiberboard boxes or drums lined with PVC bags. Net weight per package: 10kg/20kg/50kg
Instruction for storage
Seal it and store in dry place.

 
Ethyl Cellulose for industrial Usage

Introduction
Name: Ethyl Cellulose
Abbreviation: EC
Structural formula:In the formula, n stands for degree of polymerization and R for –H or –C2H5.

Characteristics:
Ethyl Cellulose is a kind of white grains or powder, having no smell or tastes. Its 5% soliquoid shows neutral to litmus test paper. Its specific density 1.07~1.18, heat distortion point: 135~155degree centigrade, and fire point: 330~360 degree centigrade. Ethyl Cellulose has good stability against light, heat, oxygen and wetness, and is stable to chemicals. It is resistant to alkali, dilute acid and salting liquid, soluble in some organic solvents, such as alcohol, ether, ketone, ester, aromatic hydrocarbon and halohydrocarbon, etc, and compatible with many celluloses, resin and nearly all plasticizers. Ethyl Cellulose has low combustibility, small hydroscopicity and good electric behavior. Its thin film and plastics have good mechanical strength and flexibility in a wide range of temperature.
Technical requirements:
Ethyl Cellulose conforms to Chinese Pharmacopoeia 2000 edition, American Pharmacopoeia USP24/NF19 standard and European Pharmacopoeia EP4.

1. Appearance:White or even yellowing powder or grains, without any smell or taste.
2. Technical Index

Item

Index

K type

N type

T type

Content of ethoxy, %

44.0~47.9

48.0~49.5

49.6~51.0

Viscosity (ethanol-toluene solvent, weight, ratio)mPas

Conform to the requirements of table 2

Residue on ignition, % <=

0.4

Loss on drying %

3.0

Heavy metal %

0.0020

Arsenic salt %

0.0002

3. Viscosity Specification
Level

Specific range

Level

Specific range

7

5.6~8.4

100

80~120

10

9~11

150

135~165

15

13.5~16.5

200

180~220

20

18~22

250

221~270

30

27~33

300

271~330

50

45~55

 

 

Note: Provided that buyers have other requirements, negotiation might be necessary between Supplier and Buyer.
Usage
Due to its insolubility in water, ethyl cellulose is mainly used as tablet adhesive and thin film coating material, etc. It is also used as retarding agent for aggregate to make various types of aggregate slow-release pills; as slow-release agent or slow-release pills for compound material when making coat; as microcapsule material to make the medical effect release continuously, and avoid the preaction of water soluble medicine. It can be too used in any type of medicine as dispersing agent, stabilizer and water retention agent to prevent medicine from absorption and deterioration, enhance the safe storage and stability of pills. It can even be used as adhesive, slow-release agent and moisture-repellant agent for vitamine pills and mineral pills.

Instruction for usage
While padding, add Ethyl Cellulose slowly into the container with solvent until it is fully wetted and dissolved.
Package
It is packed in paper bags, fiberboard boxes or drums lined with PVC bags. Net weight per package: 10kg/20kg/50kg
Instruction for storage
Seal it and store in dry place.